The shooting was reported at 12:29 p.m. at the dispensary in the 18000 block of Ventura Blvd., according to a desk officer at the Los Angeles Police Department's Operations Center.
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Brian Garcia, 28, died at the scene, the Los Angeles County coroner's office reported. His city of residence was not known.
Two men were being sought in connection with the crime, police said. No descriptions were available of the suspects.
Anyone with information on the case was urged to call 877-LAPD-247.