Firefighters were sent to the 1300 block of South Soto Street at about 1:15 p.m. on reports of the fire at a vacant former Bank of America building, according to the Los Angeles Fire Department.
The department assigned 97 firefighters to the blaze, who managed to extinguish the blaze just after 2:40 p.m. One firefighter suffered minor injuries while battling the fire and was taken to a hospital in fair condition, authorities said.
A man identified as a person of interest in the fire was being interviewed by police at the scene, said Brian Humphrey of the LAFD.
Soto Street was closed between Olympic Boulevard and Eight Street, and traffic was expected to be routed away from the area until LAFD operations are complete, Humphrey added. The public was advised to avoid the area until firefighters cleared the scene.
The cause of the fire was under investigation.