Jesse Cupido, 29, is set to be arraigned Wednesday at the Antelope Valley Courthouse in Lancaster on one count each of murder and possession of a firearm by a felon, according to the Los Angeles County District Attorney's Office.
Co-defendant Isabel Cortez, 25, also of Sun Valley, is charged with one count of being an accessory after the fact, according to the District Attorney's Office.
PREVIOUS COVERAGE: Motorcyclist killed in suspected road rage shooting in Lancaster; 2 arrested
California Highway Patrol officers initially responded to what was reported as a traffic collision and discovered Henry Gonzalez had been shot on the northbound Antelope Valley (14) Freeway at the Avenue L off-ramp.
Gonzalez, 37, was pronounced dead at the scene. The Los Angeles Department of Medical Examiner had no city of residency for Gonzalez.
Cupido and Cortez were arrested last Friday by the California Highway Patrol and have remained behind bars since then, jail records show.