The special weapons team was dispatched to Ocean Park at Lincoln boulevards at 12:32 p.m. to assist the sheriff's department's Major Crimes Bureau with the barricaded suspect, sheriff's Deputy Sara Rodriguez said.
The suspect, whose family members told a reporter at the scene that he is a man in his 20s, was taken into custody about 5 p.m. after he emerged shirtless and limping down an outdoor stairway, a police dog biting at one of his legs.
Rodriguez had no information about the nature of the crime that the suspect allegedly committed.
A report that he was wanted on suspicion of murder could not be immediately confirmed.
The original dispatch was to an apartment building in the 800 block of Ocean Park Boulevard, northeast corner of the busy intersection with Lincoln Boulevard.
SantaMonica: suspect brought out, was treated for small dog bite to foot pic.twitter.com/SEZGdBFiTM
According to sources at the scene, roads were closed in the area as a sheriff's helicopter orbited low, emanating order for the man to surrender.
A couple that lives in an apartment below the one where the suspect was holed up told a reporter they heard orders being shouted for the suspect to surrender between 11 and 11:30 a.m.
They called authorities and were first told to shelter in place before later being told by deputies to clear out of their apartment, they said.
Santa Monica police and fire paramedics were stationed nearby in a support role as the standoff played out.