405 Freeway crash: 3 injured, 1 critically, in multi-vehicle collision near Brentwood

Lanes closed on SB 405 Freeway
The southbound lanes of the 405 Freeway were closed following a crash near Brentwood.
LOS ANGELES - Three people were injured and a SigAlert was issued following an overnight crash on the 405 Freeway near Brentwood.
What we know:
Officials said the crash happened around 2:15 a.m. Wednesday on the southbound side of the 405 Freeway near the Getty Center off-ramp.
When California Highway Patrol officers arrived at the scene, they discovered three vehicles – a semi-truck, a white utility truck, and a gray Jeep – were involved in the collision and were blocking two lanes of the freeway.
Three people were injured and taken to area hospitals. Officials later said a 59-year-old man and 34-year-old man were in serious condition.
A third victim, a 53-year-old man, reportedly suffered a severed leg.

Lane closures were in effect for hours before all lanes reopened by 7:20 a.m.
Dig deeper:
The crash happened on the same stretch of freeway where Los Angeles Police Department Sgt. Shiou Deng and 34-year-old Jesus Garcia were killed after they were struck by a vehicle.
RELATED COVERAGE: 405 Freeway crash: LAPD sergeant among 2 dead in Brentwood multi-vehicle collision
The Source: Information from City News Service and California Highway Patrol.