Firefighters and paramedics were dispatched to the scene along Benedict Canyon and Clear View drives at 11:29 p.m. Friday, said Shawn Lenske of the Los Angeles City Fire Department.
Two people were rushed to an area hospital with minor injuries, Lenske said.
The crash was the result of street racing, according to media reports, and involved a Mercedes Benz in a fiery crash, where a white Toyota Prius also sustained some damage.
All of the victims were teenagers, according to media reports.
A watch commander from the Los Angeles Police Department's West Traffic Division could not be reached for comment.
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