Two people were burned in the fire, which was reported at 9:12 p.m. Saturday at 6528 N. Ellenview Ave., according to Margaret Stewart of the Los Angeles Fire Department. That location is on a hilly street, amidst large houses in the foothills at the western end of Victory Boulevard in the San Fernando Valley.
As tendrils of smoke remained in the sky above the wreckage, police sought a judge's approval to re-enter the house.
"It (the home) could possibly be a marijuana lab or growth, based upon what the fire department saw when they initially went in," said Los Angeles police Sgt. Greg Houser of the Topanga station.
It took 80 firefighters nearly an hour to contain the fire, she said.
"The building was fully involved upon our arrival," said Brian Humphrey of the Los Angeles Fire Department.
The raging flames and possible live downed electrical wires inside the home prompted firefighters to take up defensive positions while battling the blaze, Stewart said.
No firefighters were injured.
"There were two individuals that were apparently injured during the fire inside the house," Houser said. "They're in stable condition with burns. They got transported."
Humphrey said the county Health Department was at the scene Saturday night and that it was unclear if the city's Building and Safety Department had yet to arrive at the location.
"We're just waiting for clearance to go back inside the house and search for any evidence," Houser said.
Copyright 2015 FOX 11 Los Angeles | Download our mobile app for breaking news alerts or to watch FOX 11 News | Follow us on Facebook , Twitter and YouTube.